CRUK-CI Genomics Core Sequencing Service
If you have any questions about your submission,
please get in touch with the Genomics help desk.
Service Change
From January 2024 we will be changing how we produce FASTQ files from sequencing
runs. We are changing the Illumina conversion tool from bcl2fastq
to BCL Convert. This might change how your data is delivered
if your sequencing involved UMIs. Please visit
this help page
for the full implications of the change and links to Illumina's own documentation.
The Submission Process
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First, download a submission form from the
forms page.
There are forms on this page to submit for sequencing only (SLX), library preparation
and sequencing (LPS), and 10x single cell submissions. Download the form appropriate to
the submission you are making. Always download the newest form for
new submissions as these forms do evolve over time: older forms may no longer work.
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Complete the form carefully and accurately. There is help for each of the forms in the
help pages. When done,
upload the completed form to this application.
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If you do not already have an account for the sequencing service,
you will need to sign up before you will be able to make your submission.
Please use this page
to make a request for an account.
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The submission web application will check for common submission form errors before creating the samples
in Clarity. These checks cannot catch everything; getting submissions right
at the start is much less work for everyone involved than fixing problems after sequencing.
Refer to the help in this web application, and if in any
doubt please get in touch with the Genomics help desk.
Take particular care to make sure the indexes are correct when submitting
for sequencing only. The Genomics and Bioinformatics cores do not support demultiplexing
for a second time to fix incorrect barcodes: that will be your responsibility,
for which there is help here.
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Upload your completed submission form to this
web application.
The form will be checked for problems and any errors will be reported
back so the form can be corrected and resubmitted.
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With no reported errors in the form, simply confirm the submission and the samples are submitted
to Clarity. If your group requires submissions to Genomics to be approved, the
people who do the approval will be notified via email to confirm the submission before the samples
are queued. For groups without a dedicated approver the samples will be queued straight away.
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If there are any additional queries regarding billing or technical aspects with the submission,
the Genomics core will be in touch directly.
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Await your results!
